ASUN Antibody - #DF12563
| Product: | ASUN Antibody |
| Catalog: | DF12563 |
| Description: | Rabbit polyclonal antibody to ASUN |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 80 kDa; 80kD(Calculated). |
| Uniprot: | Q9NVM9 |
| RRID: | AB_2845525 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12563, RRID:AB_2845525.
Fold/Unfold
Cell cycle regulator Mat89Bb homolog; Chromosome 12 open reading frame 11; FLJ10630; FLJ10637; NET48; Sarcoma antigen NY SAR 95;
Immunogens
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
- Q9NVM9 INT13_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLKSGDSHLGGGSREGSFKETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDGSLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKPPEEEERKKRGRKREDKEDKSEKAVKDYEQEKSWQDSERLKGILERGKEELAEAEIIKDSPDSPEPPNKKPLVEMDETPQVEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGMETTENGKASRQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NVM9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K2 | Ubiquitination | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| Y67 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K167 | Ubiquitination | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| K295 | Ubiquitination | Uniprot | |
| K311 | Ubiquitination | Uniprot | |
| K436 | Ubiquitination | Uniprot | |
| K496 | Ubiquitination | Uniprot | |
| K507 | Ubiquitination | Uniprot | |
| R561 | Methylation | Uniprot | |
| Y591 | Phosphorylation | Uniprot | |
| K595 | Ubiquitination | Uniprot | |
| S596 | Phosphorylation | Uniprot | |
| K604 | Ubiquitination | Uniprot | |
| K611 | Sumoylation | Uniprot | |
| K611 | Ubiquitination | Uniprot | |
| S623 | Phosphorylation | Uniprot | |
| S626 | Phosphorylation | Uniprot | |
| T641 | Phosphorylation | Uniprot | |
| K648 | Ubiquitination | Uniprot | |
| S652 | Phosphorylation | Uniprot | |
| S658 | Phosphorylation | Uniprot | |
| T663 | Phosphorylation | Uniprot | |
| S678 | Phosphorylation | Uniprot |
Research Backgrounds
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Nucleus. Cytoplasm.
Note: Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
Interacts with PAFAH1B1; this interaction may be required for proper recruitment of dynein complexes to the nuclear envelope at prophase.
Belongs to the asunder family.
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