CES3 Antibody - #DF12580
| Product: | CES3 Antibody |
| Catalog: | DF12580 |
| Description: | Rabbit polyclonal antibody to CES3 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Mol.Wt.: | 62 kDa; 62kD(Calculated). |
| Uniprot: | Q6UWW8 |
| RRID: | AB_2845542 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12580, RRID:AB_2845542.
Fold/Unfold
Carboxylesterase 3; CES 3; Ces3; ES3; EST3_HUMAN; FLJ21736; Liver carboxylesterase 31 homolog;
Immunogens
- Q6UWW8 EST3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLPSKIQQWHQKQKNRKAQEDL
PTMs - Q6UWW8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| T25 | Phosphorylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| N105 | N-Glycosylation | Uniprot | |
| Y312 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
N-glycosylated.
Endoplasmic reticulum lumen.
Expressed in liver, colon and small intestine.
Belongs to the type-B carboxylesterase/lipase family.
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