Product: MTCH2 Antibody
Catalog: DF12663
Description: Rabbit polyclonal antibody to MTCH2
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 33 kDa; 33kD(Calculated).
Uniprot: Q9Y6C9
RRID: AB_2845625

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(88%), Bovine(88%), Horse(88%), Sheep(88%), Rabbit(100%)
Clonality:
Polyclonal
Specificity:
MTCH2 Antibody detects endogenous levels of total MTCH2.
RRID:
AB_2845625
Cite Format: Affinity Biosciences Cat# DF12663, RRID:AB_2845625.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

2310034D24Rik; HSPC032; Met-induced mitochondrial protein; MIMP; Mitochondrial carrier 2; Mitochondrial carrier homolog 2; MTCH2; MTCH2_HUMAN; OTTHUMP00000234441; OTTHUMP00000234442;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLKMLI

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Pig
88
Horse
88
Bovine
88
Sheep
88
Xenopus
75
Zebrafish
75
Chicken
63
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y6C9 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S6 Phosphorylation
Y23 Phosphorylation
S56 Phosphorylation
Y57 Phosphorylation
S63 Phosphorylation
T75 Phosphorylation
C79 S-Nitrosylation
S80 Phosphorylation
K90 Ubiquitination
S98 Phosphorylation
K100 Ubiquitination
K111 Ubiquitination
K122 Ubiquitination
S148 Phosphorylation
S157 Phosphorylation
S165 Phosphorylation
S283 Phosphorylation
K293 Acetylation
K293 Ubiquitination
K300 Ubiquitination

Research Backgrounds

Function:

The substrate transported is not yet known. Induces mitochondrial depolarization.

Subcellular Location:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.