TMEM106B Antibody - #DF12775
| Product: | TMEM106B Antibody |
| Catalog: | DF12775 |
| Description: | Rabbit polyclonal antibody to TMEM106B |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 31 kDa; 31kD(Calculated). |
| Uniprot: | Q9NUM4 |
| RRID: | AB_2845736 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12775, RRID:AB_2845736.
Fold/Unfold
2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344; FLJ11273; LRRGT00101; MGC33727; MGC94135; T106B_HUMAN; Tmem106b; Transmembrane protein 106B;
Immunogens
- Q9NUM4 T106B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKARLNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTTYQLGQSEYLNVLQPQQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NUM4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| G2 | Myristoylation | Uniprot | |
| K3 | Ubiquitination | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| K14 | Ubiquitination | Uniprot | |
| Y18 | Phosphorylation | Uniprot | |
| S33 | Phosphorylation | Uniprot | |
| Y50 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| Y132 | Phosphorylation | Uniprot | |
| Y135 | Phosphorylation | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| N145 | N-Glycosylation | Uniprot | |
| N151 | N-Glycosylation | Uniprot | |
| N164 | N-Glycosylation | Uniprot | |
| N183 | N-Glycosylation | Uniprot | |
| N256 | N-Glycosylation | Uniprot | |
| Y266 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.
Late endosome membrane>Single-pass type II membrane protein. Lysosome membrane>Single-pass type II membrane protein. Membrane>Lipid-anchor.
Expressed in frontal cortex.
Interacts with MAP6.
Belongs to the TMEM106 family.
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