XPO6 Antibody - #DF12799
(3)
| Product: | XPO6 Antibody |
| Catalog: | DF12799 |
| Description: | Rabbit polyclonal antibody to XPO6 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Chicken |
| Mol.Wt.: | 135 kDa, 100 kDa; 129kD(Calculated). |
| Uniprot: | Q96QU8 |
| RRID: | AB_2845760 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
XPO6 Antibody detects endogenous levels of total XPO6.
RRID:
AB_2845760
Cite Format: Affinity Biosciences Cat# DF12799, RRID:AB_2845760.
Cite Format: Affinity Biosciences Cat# DF12799, RRID:AB_2845760.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Exp6; Exportin 6; Exportin-6; RAN binding protein 20; Ran-binding protein 20; RANBP20; xpo6; XPO6_HUMAN;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- Q96QU8 XPO6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Chicken
100
Rabbit
100
Xenopus
58
Dog
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96QU8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K93 | Ubiquitination | Uniprot | |
| T152 | Phosphorylation | Uniprot | |
| T153 | Phosphorylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T201 | Phosphorylation | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| T210 | Phosphorylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S219 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| R305 | Methylation | Uniprot | |
| R307 | Methylation | Uniprot | |
| K357 | Ubiquitination | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| T585 | Phosphorylation | Uniprot | |
| T647 | Phosphorylation | Uniprot | |
| T652 | Phosphorylation | Uniprot | |
| S655 | Phosphorylation | Uniprot | |
| K717 | Ubiquitination | Uniprot | |
| K766 | Ubiquitination | Uniprot | |
| T781 | Phosphorylation | Uniprot | |
| T788 | Phosphorylation | Uniprot | |
| T804 | Phosphorylation | Uniprot | |
| K891 | Ubiquitination | Uniprot | |
| S961 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.
Subcellular Location:
Nucleus. Cytoplasm.
Note: Shuttles between the nucleus and the cytoplasm.
Subunit Structure:
Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with ACTB. Interacts with ACTB in a RanGTP-dependent manner.
Family&Domains:
Belongs to the exportin family.
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