Arp5/ACTR5 Antibody - #DF12838
| Product: | Arp5/ACTR5 Antibody |
| Catalog: | DF12838 |
| Description: | Rabbit polyclonal antibody to Arp5/ACTR5 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 68 kDa; 68kD(Calculated). |
| Uniprot: | Q9H9F9 |
| RRID: | AB_2845799 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12838, RRID:AB_2845799.
Fold/Unfold
Actin-related protein 5; actin-related protein 5 homolog (yeast); Actr5; Arp5; ARP5_HUMAN; FLJ12785; hARP5; INO80 complex subunit M; INO80M; Sarcoma antigen NY-SAR-16;
Immunogens
- Q9H9F9 ARP5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAANVFPFRDARAAPDPVLEAGPVAHGPLPVPLVLDNGSFQVRAGWACPGQDPGPEPRLQFRAVCARGRGGARGASGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFSSKLLGSTLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLSIAVEQAKQKILQAEVNLEVDVVDSKPETPDLEQLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYILDRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCASNIYVPIRLPKQASRSSDAQASSKGSAAGGGGAGEQA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H9F9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R69 | Methylation | Uniprot | |
| R73 | Methylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| K275 | Ubiquitination | Uniprot | |
| K283 | Ubiquitination | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| K294 | Ubiquitination | Uniprot | |
| K390 | Sumoylation | Uniprot | |
| S459 | Phosphorylation | Uniprot | |
| K509 | Ubiquitination | Uniprot |
Research Backgrounds
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.
Nucleus. Cytoplasm.
Note: Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988).
Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with DDB1. Interacts with ACTR8; the interaction is observed in asynchronous (interphase) cells but not in metaphase-arrested cells indicative for a possible dissociation of the INO80 complex in mitotic cells.
Belongs to the actin family. ARP5 subfamily.
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