ATL3 Antibody - #DF12843

(3)  
Product: ATL3 Antibody
Catalog: DF12843
Description: Rabbit polyclonal antibody to ATL3
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 61 kDa; 61kD(Calculated).
Uniprot: Q6DD88
RRID: AB_2845804

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(83%), Bovine(92%), Horse(92%), Sheep(92%), Rabbit(100%), Dog(83%)
Clonality:
Polyclonal
Specificity:
ATL3 Antibody detects endogenous levels of total ATL3.
RRID:
AB_2845804
Cite Format: Affinity Biosciences Cat# DF12843, RRID:AB_2845804.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

4633402C03Rik; 5730596K20Rik; AI465397; ATL3; ATLA3_HUMAN; Atlastin 3 like; Atlastin GTPase 3; Atlastin-3; AW228836; DKFZp564J0863; MGC28761;

Immunogens

Immunogen:
Uniprot:

Q6DD88(ATLA3_HUMAN) >>Visit HPA database.

Gene(ID):
ATL3(25923)
Expression:
Q6DD88 ATLA3_HUMAN:

Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level).

Sequence:
MLSPQRVAAAASRGADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEEKHCEFKQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFRTPAVLFTGIVALYIASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYRELGGAIDFGAAYVLEQASSHIGNSTQATVRDAVVGRPSMDKKAQ

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Horse
92
Bovine
92
Sheep
92
Pig
83
Dog
83
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6DD88 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S3 Phosphorylation
S12 Phosphorylation
S21 Phosphorylation
S22 Phosphorylation
K23 Ubiquitination
S38 Phosphorylation
Y85 Phosphorylation
S93 Phosphorylation
K130 Ubiquitination
K239 Methylation
K239 Ubiquitination
T261 Phosphorylation
K283 Ubiquitination
K309 Ubiquitination
K315 Ubiquitination
K326 Ubiquitination
K330 Ubiquitination
K341 Ubiquitination
S342 Phosphorylation
T347 Phosphorylation
K360 Ubiquitination
S379 Phosphorylation
K386 Ubiquitination
K391 Acetylation
K391 Ubiquitination
K400 Acetylation
K402 Acetylation
K407 Ubiquitination
K430 Ubiquitination
S535 Phosphorylation

Research Backgrounds

Function:

GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.
Note: Localizes to endoplasmic reticulum tubules and accumulates in punctuate structures corresponding to 3-way junctions, which represent crossing-points at which the tubules build a polygonal network.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level).

Subunit Structure:

Interacts with ZFYVE27.

Family&Domains:

Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.

Restrictive clause

 

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