BLMH Antibody - #DF12855
| Product: | BLMH Antibody |
| Catalog: | DF12855 |
| Description: | Rabbit polyclonal antibody to BLMH |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| Mol.Wt.: | 50 kDa; 53kD(Calculated). |
| Uniprot: | Q13867 |
| RRID: | AB_2845816 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12855, RRID:AB_2845816.
Fold/Unfold
BH; Bleomycin hydrolase; BLM hydrolase; BLMH; BLMH_HUMAN; BMH; EC 3.4.22.40;
Immunogens
- Q13867 BLMH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13867 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| K10 | Acetylation | Uniprot | |
| K10 | Ubiquitination | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| T249 | Phosphorylation | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| K267 | Ubiquitination | Uniprot | |
| K279 | Acetylation | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| Y280 | Phosphorylation | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| Y284 | Phosphorylation | Uniprot | |
| Y288 | Phosphorylation | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K309 | Ubiquitination | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K317 | Ubiquitination | Uniprot | |
| K330 | Ubiquitination | Uniprot | |
| K391 | Acetylation | Uniprot | |
| K391 | Ubiquitination | Uniprot |
Research Backgrounds
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
Cytoplasm.
Homohexamer.
Belongs to the peptidase C1 family.
Restrictive clause
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For Research Use Only.
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