Calumenin Antibody - #DF12876
| Product: | Calumenin Antibody |
| Catalog: | DF12876 |
| Description: | Rabbit polyclonal antibody to Calumenin |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 47 kDa; 37kD(Calculated). |
| Uniprot: | O43852 |
| RRID: | AB_2845837 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12876, RRID:AB_2845837.
Fold/Unfold
CALU; CALU_HUMAN; Calumenin 1; Calumenin 2; Calumenin; Crocalbin; crocalbin-like protein; FLJ90608; IEF SSP 9302; multiple EF-hand protein; OTTHUMP00000212712; OTTHUMP00000212713; OTTHUMP00000212714; OTTHUMP00000212715;
Immunogens
Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
- O43852 CALU_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43852 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S35 | Phosphorylation | Uniprot | |
| K37 | Ubiquitination | Uniprot | |
| S44 | Phosphorylation | Q9H4B4 (PLK3) , Q9NYY3 (PLK2) | Uniprot |
| Y47 | Phosphorylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| T60 | O-Glycosylation | Uniprot | |
| T60 | Phosphorylation | Q9NYY3 (PLK2) , Q9H4B4 (PLK3) | Uniprot |
| T65 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| K70 | Sumoylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| K75 | Ubiquitination | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| T89 | Phosphorylation | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| K98 | Ubiquitination | Uniprot | |
| Y106 | Phosphorylation | Uniprot | |
| R111 | Methylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| Y129 | Phosphorylation | Uniprot | |
| N131 | N-Glycosylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| K173 | Ubiquitination | Uniprot | |
| T177 | Phosphorylation | Q9H4B4 (PLK3) | Uniprot |
| Y185 | Phosphorylation | Uniprot | |
| Y187 | Phosphorylation | Uniprot | |
| T196 | Phosphorylation | Q9H4B4 (PLK3) , Q9NYY3 (PLK2) | Uniprot |
| K248 | Methylation | Uniprot | |
| T254 | Phosphorylation | Q9H4B4 (PLK3) | Uniprot |
| K255 | Ubiquitination | Uniprot | |
| S261 | O-Glycosylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| Y263 | Phosphorylation | Uniprot | |
| Y275 | Phosphorylation | Uniprot | |
| S277 | Phosphorylation | Uniprot | |
| K281 | Ubiquitination | Uniprot | |
| K287 | Sumoylation | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| K293 | Ubiquitination | Uniprot | |
| S300 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
Interacts with GGCX.
Belongs to the CREC family.
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