COG3 Antibody - #DF12905
| Product: | COG3 Antibody |
| Catalog: | DF12905 |
| Description: | Rabbit polyclonal antibody to COG3 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 94 kDa, 105 kDa; 94kD(Calculated). |
| Uniprot: | Q96JB2 |
| RRID: | AB_2845866 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12905, RRID:AB_2845866.
Fold/Unfold
COG complex subunit 3; Cog3; COG3_HUMAN; Component of golgi transport complex 3; Component of oligomeric Golgi complex 3; Conserved oligomeric Golgi complex subunit 3; OTTHUMP00000018352; p94; SEC34; SEC34 S. cerevisiae homolog of; SEC34, S. cerevisiae, homolog of; Tethering factor SEC34; Vesicle docking protein SEC34 homolog; Vesicle-docking protein SEC34 homolog;
Immunogens
Widely expressed with highest levels in pancreas and testis and lowest levels in lung.
- Q96JB2 COG3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEAALLLLPEAAAERDAREKLALWDRRPDTTAPLTDRQTDSVLELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTEDILLKGFTSLGMEEERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILNDVNSALQHLESLQKQYLFVSNKTGTLHEACEQLLKEQSELVDLAENIQQKLSYFNELETINTKLNSPTLSVNSDGFIPMLAKLDDCITYISSHPNFKDYPIYLLKFKQCLSKALHLMKTYTVNTLQTLTSQLLKRDPSSVPNADNAFTLFYVKFRAAAPKVRTLIEQIELRSEKIPEYQQLLNDIHQCYLDQRELLLGPSIACTVAELTSQNNRDHCALVRSGCAFMVHVCQDEHQLYNEFFTKPTSKLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILKNEVLEDHVQNNAEQLGAFAAGVKQMLEDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKKVPSEASFSDVHLEEGESNSLTKSGSTESLNPRPQTTISPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQGLSQEALSACIQSLLGASESISKNKTQIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRDAAFKILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHYLDSKKDVDRHLKSACEQFIQQQTKLFVEQLEEFMTKVSALKTMASQGGPKYTLSQQPWAQPAKVNDLAATAYKTIKTKLPVTLRSMSLYLSNKDTEFILFKPVRNNIQQVFQKFHALLKEEFSPEDIQIIACPSMEQLSLLLLVSK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96JB2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| K126 | Acetylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| T214 | Phosphorylation | Uniprot | |
| T273 | Phosphorylation | Uniprot | |
| S511 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| S516 | Phosphorylation | Uniprot | |
| T529 | Phosphorylation | Uniprot | |
| S531 | Phosphorylation | Uniprot | |
| S533 | Phosphorylation | Uniprot | |
| S536 | Phosphorylation | Uniprot | |
| T604 | Phosphorylation | Uniprot | |
| S636 | Phosphorylation | Uniprot | |
| K648 | Ubiquitination | Uniprot | |
| S663 | Phosphorylation | Uniprot | |
| K694 | Ubiquitination | Uniprot | |
| T717 | Phosphorylation | Uniprot | |
| K723 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in ER-Golgi transport.
Golgi apparatus>Golgi stack membrane>Peripheral membrane protein.
Note: Associated with the peripheral membrane of cis/medial cisternae.
Widely expressed with highest levels in pancreas and testis and lowest levels in lung.
Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Interacts with TMEM115.
Belongs to the COG3 family.
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