DDAH2 Antibody - #DF12931
| Product: | DDAH2 Antibody |
| Catalog: | DF12931 |
| Description: | Rabbit polyclonal antibody to DDAH2 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 40 kDa; 30kD(Calculated). |
| Uniprot: | O95865 |
| RRID: | AB_2845892 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12931, RRID:AB_2845892.
Fold/Unfold
DDAH; DDAH II; DDAH-2; DDAH2; DDAH2_HUMAN; DDAHII; Dimethylargininase 2; Dimethylargininase-2; Dimethylarginine dimethylaminohydrolase 2; Dimethylarginine dimethylaminohydrolase II; G6a; N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; NG dimethylarginine dimethylamino hydrolase homolog; NG30; OTTHUMP00000029307; OTTHUMP00000029310; OTTHUMP00000174488; OTTHUMP00000174489; Protein G6a; S phase protein; S-phase protein;
Immunogens
Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain.
- O95865 DDAH2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95865 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T3 | Phosphorylation | Uniprot | |
| S22 | Phosphorylation | Uniprot | |
| K51 | Acetylation | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| T127 | Phosphorylation | Uniprot | |
| T132 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| S263 | Phosphorylation | Uniprot | |
| S285 | Phosphorylation | Uniprot |
Research Backgrounds
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
Cytoplasm. Mitochondrion.
Note: Translocates from cytosol to mitochondrion upon IL-1beta stimulation in chondrocytes.
Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain.
Belongs to the DDAH family.
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