DNAJC21 Antibody - #DF12950
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12950, RRID:AB_2845911.
Fold/Unfold
DJC21_HUMAN; DnaJ homolog subfamily A member 5; DnaJ homolog subfamily C member 21; DNAJA5; dnajc21; GS3; JJJ1; Protein GS3;
Immunogens
- Q5F1R6 DJC21_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKCHYEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELESVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDEAEDAELYDDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKLSKKQKKKKQKPAQNYDDNFNVNGPGEGVKVDPEDTNLNQDSAKELEDSPQENVSVTEIIKPCDDPKSEAKSVPKPKGKKTKDMKKPVRVPAEPQTMSVLISCTTCHSEFPSRNKLFDHLKATGHARAPSSSSLNSATSSQSKKEKRKNR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5F1R6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K2 | Methylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| K167 | Ubiquitination | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| Y275 | Phosphorylation | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| S283 | Phosphorylation | Uniprot | |
| S302 | Phosphorylation | Uniprot | |
| S370 | Phosphorylation | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| Y397 | Phosphorylation | Uniprot | |
| S423 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| S436 | Phosphorylation | Uniprot | |
| S449 | Phosphorylation | Uniprot | |
| K460 | Acetylation | Uniprot | |
| S511 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| S523 | Phosphorylation | Uniprot |
Research Backgrounds
May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S rRNA.
Cytoplasm. Nucleus. Nucleus>Nucleolus.
Note: Within the nucleus, localizes primarily to the nucleolus.
Expressed in brain, placenta, kidney and pancreas.
Interacts with HSPA8, PA2G4 and ZNF622.
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