Product: DPP3 Antibody
Catalog: DF12959
Description: Rabbit polyclonal antibody to DPP3
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 69 kDa; 83kD(Calculated).
Uniprot: Q9NY33
RRID: AB_2845920

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
DPP3 Antibody detects endogenous levels of total DPP3.
RRID:
AB_2845920
Cite Format: Affinity Biosciences Cat# DF12959, RRID:AB_2845920.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase 3; Dipeptidyl peptidase III; DPP III; dpp3; DPP3_HUMAN; DPPIII; EC 3.4.14.4;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9NY33 DPP3_HUMAN:

Detected in placenta (at protein level) (PubMed:3233187). Detected in erythrocytes (at protein level) (PubMed:1515063).

Sequence:
MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Rabbit
100
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NY33 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S27 Phosphorylation
T29 Phosphorylation
K113 Ubiquitination
S130 Phosphorylation
K165 Ubiquitination
K202 Ubiquitination
K209 Ubiquitination
S218 Phosphorylation
K233 Ubiquitination
K235 Ubiquitination
K257 Ubiquitination
K264 Ubiquitination
S272 Phosphorylation
T286 Phosphorylation
S289 Phosphorylation
K294 Acetylation
K294 Ubiquitination
S297 Phosphorylation
K337 Ubiquitination
K342 Ubiquitination
K405 Ubiquitination
S408 Phosphorylation
K423 Ubiquitination
T425 Phosphorylation
K459 Ubiquitination
K466 Ubiquitination
K498 Ubiquitination
K615 Ubiquitination
K629 Ubiquitination
S630 Phosphorylation
T631 Phosphorylation
Y641 Phosphorylation
K670 Ubiquitination
T677 Phosphorylation
S682 Phosphorylation
S692 Phosphorylation
R698 Methylation
S699 Phosphorylation
S701 Phosphorylation
K727 Ubiquitination

Research Backgrounds

Function:

Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (in vitro).

Subcellular Location:

Cytoplasm>Cytosol.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in placenta (at protein level). Detected in erythrocytes (at protein level).

Family&Domains:

Belongs to the peptidase M49 family.

Restrictive clause

 

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