Product: EXPH5 Antibody
Catalog: DF12992
Description: Rabbit polyclonal antibody to EXPH5
Application: WB IHC
Reactivity: Human
Mol.Wt.: 230 kDa; 223kD(Calculated).
Uniprot: Q8NEV8
RRID: AB_2845953

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
EXPH5 Antibody detects endogenous levels of total EXPH5.
RRID:
AB_2845953
Cite Format: Affinity Biosciences Cat# DF12992, RRID:AB_2845953.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DKFZp586F1223; DKFZp781H0795; Exophilin 5; Exophilin5; KIAA0624; MGC133291; MGC134967; SLAC2-B; SLAC2B; slp homolog lacking C2 domains b; synaptotagmin-like homologue lacking C2 domains b; synaptotagmin-like protein homolog lacking C2 domains b;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q8NEV8 EXPH5_HUMAN:

Expressed in keratinocytes.

Sequence:
MTKVPPAFDFSFLNDEEARKILQVLERNEELQRAEKDRISKLQKTKRDIRWLQGVTGEWFEEIQRKKFCNETDVSQMLKQPLTYRLSKEMAKNDPIELPTSRSKNVTNQKKPTPFSSRMSFRSSFASLFSFRKSGKETSKLPSLGQKGCDGHAGPPMPVRGAAVQAKIYNSPLENHLVDSTFVPKPAVMREESGMPPPWDASLLENEFFQVLDDLDSKLAQEQSASSVNTRTPLNYGSRTQFGHFYSSGNRHGNITERHKKHYNETSNMSIYDILRPGTPREGFKTFSPRTSTIYDMYRTREPRVFKEDYVQKNTFGSTSLCFDSRQRSALPATGHFTARSLHFPATTQSKSGFIPPRHQQSPKRTPLSSIIWNRSDSSRDRENQEEFLRAPSPMEIDPADKYVYPRGFQENKRYESYHSQNVYQRVSLNAPMENAMSPDTFENSENMPFYHQSNTFTRSFFSNTFGRSGEQRRFGQGPFWGQEKGHSFWSDFHRSRKSFSSSDRDFEMISMEANSVSAIHGHNVSSEHWESFSSGYGTDVSRGQEEPHPWQFDFQRSTLDSMVVSHGNETQLTPHFGTPNVCSMTGSSYHVKSSELVSQQDSSPVEVHINKEASSFGIAQTLASSFKTSFSQISDDRRNPQSPNLQNPTVTLQKIFPNKPASHPMRSHTEVTVTSSNSVDSLPLAKSQPNILVTEVNNEKDLNESISEEDKQLSKMDQTNKAGEIPQPVSQTGISNSLPDFQNPLSQDSAKSNGFGFNASTIISSKKSPRVFSRKDTSKMYIPHTDKSNDIKQDKRFTENRKLGSTASLPFIQEHRTPPSFPRTDQGCHQELTVNNEDISRIITNNHWSSALTDTQNAQYSKCKLTPGHKTSCDSLDLSSAALPDSSPSKNSSLDAPVVPSTTVFSRRSPSDKDPSLGEREEKDNAGKNQKNQFIVSHSENQERNDSPVPTHDEVVDVKCHSHSPFRNERGKGKIRHHISCIEKLSKTESISVPTSDHRSLIEANQSNSKVSELDTIYCTLPRKSSSFLIHGRQSGSKIMAASLRNGPPPFQIKNNVEDAMGNYMLNKFSPSSPESANECSKVLSDSALEAPEATERMTNVKSSGSTSVRKGPLPFLINRAMSCPSGEPHASTGREGRKKPLTSGMDASELTPRAWERIISPVESDSSVRDCSLTKRQHQKENFQEYTEKEGKMAASRRSVFALSNEDPLPFCSDLSGKERGKTLHKVKTTSTFSVSGDEDNVKCLEVVSIYYTLPRKPSKKFCNLLQQYTQNTNLLIESPQVETETFPNALEKDKQNYSTREQSGTPSCENLKMSVNSDQTLTTENMTAFRLSNRGPLAPTLQEMASVEAAVSLPEEESKAREIFSDNLAKTPLGDSENKKERGKKLQSETLHTSLMLQRKNVSEEKSENCQQSINSSNSGPSSLPALSEVNIGNSQTRRSSWECTGSGRAIPFTGSGKCPQKDHTSTAVGDGSSGSQPREGRGDIGTNCQKMTNKTLSHSESQVFALTPALHKLQLGEETQSDEPNLESLQSEPRELPQRSQEANMTESRKAEDEMQKSAWDQPSLPEGNKNKTNLDDLVKGENRSSVKHRLAAMSKASRKFPAKDVSPRRHVATIFPQSGSRSGFDHLSLGTVECNPLFPEPTPKSAESIGESRLSENGKHVKKSENLLPITVLPNREPSTHVSNQKSNSISQRHQNEFKNVSESPSKHENSKDVTAAQNLVRESGAPSPITFTSLREAEFSDNQRRLSPPFPLEPAQKSRVSSPLASFLQQQRSASSLEWEPEPHLYRSKSLKSINVHGDLLRKSHPPKVRERHFSESTSIDNALSRLTLGNEFSVNNGYSRRFRSFSELPSCDGNESWAYRSGTKTGPRSAISIYRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDLRNPPNPSESLSSNSPSSQVPEDGLSPSEPLNIYEDDPVDSNCDTDTTTDDEYYLDENDKESEL

PTMs - Q8NEV8 As Substrate

Site PTM Type Enzyme
K92 Ubiquitination
S124 Phosphorylation
K140 Ubiquitination
S247 Phosphorylation
T293 Phosphorylation
Y295 Phosphorylation
T300 Phosphorylation
K307 Ubiquitination
S318 Phosphorylation
S320 Phosphorylation
T338 Phosphorylation
S341 Phosphorylation
K351 Ubiquitination
S362 Phosphorylation
K364 Acetylation
S393 Phosphorylation
Y403 Phosphorylation
Y405 Phosphorylation
T465 Phosphorylation
S603 Phosphorylation
S604 Phosphorylation
S635 Phosphorylation
S643 Phosphorylation
K660 Ubiquitination
S688 Phosphorylation
S706 Phosphorylation
S708 Phosphorylation
T720 Phosphorylation
S769 Phosphorylation
K776 Methylation
Y782 Phosphorylation
S806 Phosphorylation
S809 Phosphorylation
T818 Phosphorylation
T872 Phosphorylation
S876 Phosphorylation
S902 Phosphorylation
S910 Phosphorylation
S948 Phosphorylation
S963 Phosphorylation
S965 Phosphorylation
K973 Acetylation
S981 Phosphorylation
K988 Ubiquitination
T989 Phosphorylation
S1013 Phosphorylation
Y1019 Phosphorylation
S1026 Phosphorylation
S1028 Phosphorylation
K1055 Methylation
S1071 Phosphorylation
S1074 Phosphorylation
S1086 Phosphorylation
S1088 Phosphorylation
S1124 Phosphorylation
S1162 Phosphorylation
K1182 Ubiquitination
K1220 Ubiquitination
S1238 Phosphorylation
S1310 Phosphorylation
T1374 Phosphorylation
T1393 Phosphorylation
T1396 Phosphorylation
S1444 Phosphorylation
S1450 Phosphorylation
T1457 Phosphorylation
S1459 Phosphorylation
S1505 Phosphorylation
K1584 Ubiquitination
S1602 Phosphorylation
S1611 Phosphorylation
S1623 Phosphorylation
S1707 Phosphorylation
S1716 Phosphorylation
S1733 Phosphorylation
S1753 Phosphorylation
S1764 Phosphorylation
S1767 Phosphorylation
S1768 Phosphorylation
S1779 Phosphorylation
Y1792 Phosphorylation
S1796 Phosphorylation
S1799 Phosphorylation
S1821 Phosphorylation
S1840 Phosphorylation
S1851 Phosphorylation
S1853 Phosphorylation
Y1886 Phosphorylation

Research Backgrounds

Function:

May act as Rab effector protein and play a role in vesicle trafficking.

Tissue Specificity:

Expressed in keratinocytes.

Subunit Structure:

Interacts with RAB27A.

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