GPR177 Antibody - #DF13051
| Product: | GPR177 Antibody |
| Catalog: | DF13051 |
| Description: | Rabbit polyclonal antibody to GPR177 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 62 kDa; 62kD(Calculated). |
| Uniprot: | Q5T9L3 |
| RRID: | AB_2846012 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13051, RRID:AB_2846012.
Fold/Unfold
C1orf139; DKFZp686I0788; Evenness interrupted, Drosophila, homolg of; EVI; FLJ23091; G protein coupled receptor 177; GPR 177; Integral membrane protein GPR177; MGC131760; MGC14878; mig-14; MRP; Protein evenness interrupted homolog; Protein wntless homolog; Putative NF-kappa-B-activating protein 373; Putative NFkB activating protein 373; WLS; WLS_HUMAN; wntless homolog (Drosophila); Wntless homolog; wntless Wnt ligand secretion mediator; Wntless, Drosophila, homolog of;
Immunogens
- Q5T9L3 WLS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDARKNHHKTKWFVPWGPNHCDKIRDIEEAIPREIEANDIVFSVHIPLPHMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDAFAEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYECDVLPFMEIGSVAHKFYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDIGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5T9L3 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K61 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| K161 | Ubiquitination | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| K206 | Ubiquitination | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| T257 | Phosphorylation | Uniprot | |
| K410 | Ubiquitination | Uniprot | |
| S412 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| K419 | Ubiquitination | Uniprot |
Research Backgrounds
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).
Golgi apparatus membrane>Multi-pass membrane protein. Cytoplasmic vesicle membrane>Multi-pass membrane protein. Cell membrane>Multi-pass membrane protein. Endoplasmic reticulum membrane>Multi-pass membrane protein. Golgi apparatus membrane>Multi-pass membrane protein. Early endosome membrane>Multi-pass membrane protein.
Note: Co-localizes with the adaptin AP2A2 at distinct punctae.
Interacts with WNT3A. Interacts with WNT1, WNT3 and WNT5A (By similarity).
Belongs to the wntless family.
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