HEATR2 Antibody - #DF13056
| Product: | HEATR2 Antibody |
| Catalog: | DF13056 |
| Description: | Rabbit polyclonal antibody to HEATR2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Pig |
| Mol.Wt.: | 93 kDa; 94kD(Calculated). |
| Uniprot: | Q86Y56 |
| RRID: | AB_2846017 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13056, RRID:AB_2846017.
Fold/Unfold
BC053401; C76907; FLJ20397; FLJ25564; FLJ31671; FLJ39381; HEAT repeat containing protein 2; HEAT repeat-containing protein 2; HEAT2_HUMAN; HEATR2; hypothetical protein FLJ20397; MGC125214; MGC60818;
Immunogens
Expressed in nasal epithelium and lung epithelium by ciliated cells (at protein level).
- Q86Y56 DAAF5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAALGVAEAVAAPHPAEGAETAEAVELSRALSRLLPGLEADSKPGRRRALEALRRALEEPGPAADPTAFQGPWARLLLPRLLRCLSDPAEGCRALAVHLLDLGLRRAARPRDALPRLLPALAARLAGPVPARRPPEACEELRLALVQLLGLAVDLCGAALAPHLDDALRALRCSLLDPFAAVRRESCSCAAALAQATPDHFHMQSESLIGPLMQTISHQHWKVRVAAIEATGAVIHFGNGKSVDDVLSHFAQRLFDDVPQVRRAVASVVGGWLLCLRDRYSFFHKLIPLLLSSLNDEVPEVRQLAASLWEDVGLQWQKENEEDLKDKLDFAPPTPPHYPPHERRPVLGCRELVFRNLSKILPALCHDITDWVVGTRVKSAQLLPVLLLHAEDHATQHLEVVLRTLFQACTDEEAAVVQSCTRSAELVGTFVSPEVFLKLILSTLKKTPSASGLLVLASAMRGCPREALQPHLAAIATELAQAHICQASENDLYLERLLLCVQALVSVCHEDCGVASLQLLDVLLTIVALAGATGLRDKAQETMDSLAMVEGVSSCQDLYRKHIGPLLERVTASHLDWTAHSPELLQFSVIVAQSGPALGEALPHVVPTLRACLQPSQDPQMRLKLFSILSTVLLRATDTINSQGQFPSYLETVTKDILAPNLQWHAGRTAAAIRTAAVSCLWALTSSEVLSAEQIRDVQETLMPQVLTTLEEDSKMTRLISCRIINTFLKTSGGMTDPEKLIRIYPELLKRLDDVSNDVRMAAASTLVTWLQCVKGANAKSYYQSSVQYLYRELLVHLDDPERAIQDAILEVLKEGSGLFPDLLVRETEAVIHKHRSATYCEQLLQHVQAVPATQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q86Y56 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K43 | Sumoylation | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| T334 | Phosphorylation | Uniprot | |
| K359 | Ubiquitination | Uniprot | |
| K378 | Ubiquitination | Uniprot | |
| K445 | Ubiquitination | Uniprot | |
| K446 | Ubiquitination | Uniprot | |
| S451 | Phosphorylation | Uniprot | |
| K561 | Ubiquitination | Uniprot | |
| K655 | Ubiquitination | Uniprot | |
| K715 | Ubiquitination | Uniprot | |
| S721 | Phosphorylation | Uniprot | |
| T727 | Phosphorylation | Uniprot | |
| K730 | Ubiquitination | Uniprot | |
| T731 | Phosphorylation | Uniprot | |
| S732 | Phosphorylation | Uniprot | |
| K740 | Ubiquitination | Uniprot | |
| K750 | Ubiquitination | Uniprot | |
| K780 | Ubiquitination | Uniprot | |
| K834 | Ubiquitination | Uniprot | |
| C841 | S-Nitrosylation | Uniprot |
Research Backgrounds
Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility.
Cytoplasm. Cytoplasmic granule.
Note: Observed only in the cytoplasm of ciliated cells and absent from cilia.
Expressed in nasal epithelium and lung epithelium by ciliated cells (at protein level).
Interacts with DNAI2; probably involved in outer arm dynein assembly.
Belongs to the DNAAF5 family.
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