IGSF21 Antibody - #DF13085
Product: | IGSF21 Antibody |
Catalog: | DF13085 |
Description: | Rabbit polyclonal antibody to IGSF21 |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Xenopus |
Mol.Wt.: | 50 kDa; 52kD(Calculated). |
Uniprot: | Q96ID5 |
RRID: | AB_2846045 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13085, RRID:AB_2846045.
Fold/Unfold
FLJ41177; IGSF 21; Immunoglobin superfamily member 21; MGC15730; RP11 121A23.1;
Immunogens
- Q96ID5 IGS21_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRTAPSLRRCVCLLLAAILDLARGYLTVNIEPLPPVVAGDAVTLKCNFKTDGRMREIVWYRVTDGGTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVVLASGNIFLNVMAPPTSIEVVAADTPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPLSEPPAASSGPLQDSRPFRSLLHRDLDDTKMQKSLSLLDAENRGGRPYTERPSRGLTPDPNILLQPTTENIPETVVSREFPRWVHSAEPTYFLRHSRTPSSDGTVEVRALLTWTLNPQIDNEALFSCEVKHPALSMPMQAEVTLVAPKGPKIVMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSAEFDGKELVLERVPAELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSNGSIGPTGARLTLVLALTVILELT
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96ID5 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S209 | Phosphorylation | Uniprot | |
S280 | Phosphorylation | Uniprot | |
S389 | Phosphorylation | Uniprot | |
S446 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2.
Cell junction>Synapse>Postsynaptic cell membrane>Lipid-anchor.
Interacts (Ig-like 1 domain) with NRXN2 (via Laminin G-like 1 domain) in a trans-interaction manner.
Ig-like 1 domain is indispensable for synaptogenic activity whereas Ig-like 2 domain is secondarily responsible for the activity.
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