KCNE4 Antibody - #DF13104
Product: | KCNE4 Antibody |
Catalog: | DF13104 |
Description: | Rabbit polyclonal antibody to KCNE4 |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Rabbit, Dog, Chicken |
Mol.Wt.: | 28 kDa; 24kD(Calculated). |
Uniprot: | Q8WWG9 |
RRID: | AB_2846064 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13104, RRID:AB_2846064.
Immunogens
Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.
- Q8WWG9 KCNE4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHFLTIYPNCSSGVVRAQSRTEQKNPLGLDDLGIQNLGQTVSLAPAVEAASMLKMEPLNSTHPGTAASSSPLESRAAGGGSGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPVVSGLRSVQVPLMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLTIQEEGADDELEETSETPLNESSEGSSENIHQNS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WWG9 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S119 | Phosphorylation | Uniprot | |
Y124 | Phosphorylation | Uniprot |
Research Backgrounds
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current.
Membrane>Single-pass membrane protein.
Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.
Interacts with KCNQ1; impairs KCNQ1 localization in lipid rafts and inhibits voltage-gated potassium channel activity.
Belongs to the potassium channel KCNE family.
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