MYOZ1 Antibody - #DF13172
| Product: | MYOZ1 Antibody |
| Catalog: | DF13172 |
| Description: | Rabbit polyclonal antibody to MYOZ1 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 32 kDa; 32kD(Calculated). |
| Uniprot: | Q9NP98 |
| RRID: | AB_2846132 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13172, RRID:AB_2846132.
Fold/Unfold
actinin- and telethonin-binding protein; Calsarcin 2; Calsarcin-2; CS 2; FATZ; Filamin, actinin and telethonin binding protein; Filamin-; MYOZ; MYOZ1; MYOZ1_HUMAN; Myozenin-1; Protein FATZ;
Immunogens
Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
- Q9NP98 MYOZ1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NP98 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S15 | Phosphorylation | Uniprot | |
| S16 | Phosphorylation | Uniprot | |
| T23 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| T93 | Phosphorylation | Uniprot | |
| Y127 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| T159 | Phosphorylation | Uniprot | |
| T165 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| Y218 | Phosphorylation | Uniprot | |
| T224 | Phosphorylation | Uniprot | |
| Y228 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot |
Research Backgrounds
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Nucleus. Cell projection>Pseudopodium.
Note: Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.
Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
Interacts with ACTN2, ACTN3, FLNA, FLNB, FLNC, LDB3, PPP3CA and TCAP. Interacts via its C-terminal region with MYOT.
Belongs to the myozenin family.
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