Myozenin2 Antibody - #DF13173
| Product: | Myozenin2 Antibody |
| Catalog: | DF13173 |
| Description: | Rabbit polyclonal antibody to Myozenin2 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Horse, Rabbit, Dog |
| Mol.Wt.: | 30 kDa; 30kD(Calculated). |
| Uniprot: | Q9NPC6 |
| RRID: | AB_2846133 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13173, RRID:AB_2846133.
Fold/Unfold
C4orf5; Calcineurin binding protein calsarcin 1; Calsarcin 1; Calsarcin-1; Calsarcin1; CMH16; CS 1; CS1; FATZ related protein 2; FATZ-related protein 2; Muscle specific protein; MYOZ 2; MYOZ2; MYOZ2_HUMAN; Myozenin-2; Myozenin2;
Immunogens
- Q9NPC6 MYOZ2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKMRQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NPC6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S51 | Phosphorylation | Uniprot | |
| T69 | Phosphorylation | Uniprot | |
| Y75 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| T107 | Phosphorylation | Uniprot | |
| T111 | Phosphorylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| Y127 | Phosphorylation | Uniprot | |
| Y182 | Phosphorylation | Uniprot | |
| T235 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot |
Research Backgrounds
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Cytoplasm>Myofibril>Sarcomere>Z line.
Note: Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
Expressed specifically in heart and skeletal muscle.
Interacts via its C-terminus with spectrin repeats 3 and 4 of ACTN2. Interacts with ACTN1, LDB3, MYOT and PPP3CA.
Belongs to the myozenin family.
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