GOLPH4 Antibody - #DF13320
| Product: | GOLPH4 Antibody |
| Catalog: | DF13320 |
| Description: | Rabbit polyclonal antibody to GOLPH4 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 81kDa; 82kD(Calculated). |
| Uniprot: | O00461 |
| RRID: | AB_2846339 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13320, RRID:AB_2846339.
Fold/Unfold
130 kDa golgi localized phosphoprotein; cis; cis Golgi localized calcium binding protein; GIMPc; Golgi integral membrane protein 4; Golgi integral membrane protein; Golgi phosphoprotein 4; Golgi phosphoprotein of 130 kDa; Golgi-localized phosphoprotein of 130 kDa; GOLI4_HUMAN; golim4; GOLPH 4; GPP 130; GPP130; P 138; P138; type II Golgi membrane protein;
Immunogens
- O00461 GOLI4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00461 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| G2 | Myristoylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K141 | Acetylation | Uniprot | |
| K170 | Sumoylation | Uniprot | |
| T194 | O-Glycosylation | Uniprot | |
| T216 | O-Glycosylation | Uniprot | |
| S222 | O-Glycosylation | Uniprot | |
| T229 | O-Glycosylation | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| T270 | O-Glycosylation | Uniprot | |
| T276 | O-Glycosylation | Uniprot | |
| S283 | O-Glycosylation | Uniprot | |
| S283 | Phosphorylation | Uniprot | |
| T302 | O-Glycosylation | Uniprot | |
| T308 | O-Glycosylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| Y394 | Phosphorylation | Uniprot | |
| S396 | O-Glycosylation | Uniprot | |
| S396 | Phosphorylation | Uniprot | |
| S405 | O-Glycosylation | Uniprot | |
| Y407 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| S583 | Phosphorylation | Uniprot | |
| Y613 | Phosphorylation | Uniprot | |
| T626 | Phosphorylation | Uniprot | |
| T640 | Phosphorylation | Uniprot | |
| Y641 | Phosphorylation | Uniprot | |
| Y673 | Phosphorylation | Uniprot | |
| S690 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi.
Phosphorylated probably by c-AMP-dependent kinases in its lumenal part.
O-glycosylated; modified by sialic acid residues.
N-glycosylated; N-glycans are probably of the complex type and modified by sialic acid residues.
Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein. Endosome membrane>Single-pass type II membrane protein. Membrane>Lipid-anchor.
Note: Localizes to cis and medial Golgi cisternae. Probably cycles between early Golgi and distal compartments like endosome.
Belongs to the GOLIM4 family.
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