RBM3 Antibody - #DF13353
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13353, RRID:AB_2846372.
Fold/Unfold
2600016C11Rik; IS1 RNPL; MGC105811; MGC118410; OTTHUMP00000025800; OTTHUMP00000025802; OTTMUSP00000019634; OTTMUSP00000019635; OTTMUSP00000019636; Putative RNA binding protein 3; Putative RNA-binding protein 3; Rbm3; RBM3_HUMAN; RNA binding motif (RNP1, RRM) protein 3; RNA binding motif protein 3; RNA-binding motif protein 3; RNA-binding protein 3; RNPL; RP23-27I6.7;
Immunogens
- P98179 RBM3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASVAMRAMNGESLDGRQIRVDHAGKSARGTRGGGFGAHGRGRSYSRGGGDQGYGSGRYYDSRPGGYGYGYGRSRDYNGRNQGGYDRYSGGNYRDNYDN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P98179 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| R47 | Methylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| R65 | Methylation | Uniprot | |
| S71 | Phosphorylation | Uniprot | |
| R87 | Methylation | Uniprot | |
| R90 | Methylation | Uniprot | |
| R99 | Methylation | Uniprot | |
| R101 | Methylation | Uniprot | |
| Y103 | Phosphorylation | Uniprot | |
| R105 | Methylation | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| R116 | Methylation | Uniprot | |
| Y117 | Phosphorylation | Uniprot | |
| Y118 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| R121 | Methylation | Uniprot | |
| Y125 | Phosphorylation | Uniprot | |
| Y127 | Phosphorylation | Uniprot | |
| Y129 | Phosphorylation | Uniprot | |
| R131 | Methylation | Uniprot | |
| S132 | Phosphorylation | Uniprot | |
| R133 | Methylation | Uniprot | |
| Y135 | Phosphorylation | Uniprot | |
| R138 | Methylation | Uniprot | |
| Y143 | Phosphorylation | Uniprot | |
| R145 | Methylation | Uniprot | |
| Y146 | Phosphorylation | Uniprot | |
| S147 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| Y151 | Phosphorylation | Uniprot | |
| Y155 | Phosphorylation | Uniprot |
Research Backgrounds
Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation (By similarity).
Arg-105 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated.
Nucleus. Cytoplasm. Cell projection>Dendrite.
Note: Localizes in mRNA granules in dentrites.
Interacts with RPL4. Associates with the 60S ribosomal subunits in an RNA-independent manner. Associates with ribosomes (By similarity).
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