XLF Antibody - #DF13366
| Product: | XLF Antibody |
| Catalog: | DF13366 |
| Description: | Rabbit polyclonal antibody to XLF |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Xenopus |
| Mol.Wt.: | 33kDa; 33kD(Calculated). |
| Uniprot: | Q9H9Q4 |
| RRID: | AB_2846385 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13366, RRID:AB_2846385.
Fold/Unfold
Cernunnos; FLJ12610; NHEJ 1; Nhej1; NHEJ1, S. cerevisiae, homolog of; NHEJ1_HUMAN; Non homologous end joining factor 1; Non-homologous end-joining factor 1; Nonhomologous end joining factor 1; OTTHUMP00000164168; OTTHUMP00000206275; OTTHUMP00000206279; Protein cernunnos; XLF; XRCC4 like factor; XRCC4-like factor;
Immunogens
A synthesized peptide derived from human XLF, corresponding to a region within the internal amino acids.
- Q9H9Q4 NHEJ1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKELNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWNFHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
Research Backgrounds
DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary. Binds DNA in a length-dependent manner.
Nucleus.
Ubiquitously expressed.
The coiled-coil region mediates homodimerization.
Belongs to the XLF family.
Research Fields
· Genetic Information Processing > Replication and repair > Non-homologous end-joining.
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