Synaptotagmin Antibody - #DF13380
| Product: | Synaptotagmin Antibody |
| Catalog: | DF13380 |
| Description: | Rabbit polyclonal antibody to Synaptotagmin |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 42kDa; 43kD(Calculated). |
| Uniprot: | O00445 |
| RRID: | AB_2846399 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13380, RRID:AB_2846399.
Fold/Unfold
Synaptotagmin 5; Synaptotagmin IX; Synaptotagmin V; Synaptotagmin-5; Syt5; SYT5_HUMAN; SytV;
Immunogens
- O00445 SYT5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00445 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T15 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| T59 | Phosphorylation | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| K268 | Acetylation | Uniprot | |
| Y278 | Phosphorylation | Uniprot |
Research Backgrounds
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity).
Cytoplasmic vesicle>Secretory vesicle>Synaptic vesicle membrane>Single-pass membrane protein. Recycling endosome membrane>Single-pass membrane protein.
Note: In mast cells, localizes to the endocytic recycling compartment.
Homodimer (By similarity). Interacts with both alpha- and beta-tubulin (By similarity).
Belongs to the synaptotagmin family.
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