TOM1L2 Antibody - #DF13443
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13443, RRID:AB_2846462.
Fold/Unfold
FLJ32746; Srebf1; Target of Myb-like protein 2; Target of myb1 like 2; Target of myb1-like 2 (chicken); TM1L2_HUMAN; TOM1; TOM1-like 2; TOM1-like protein 2; TOM1L 2; Tom1l2;
Immunogens
- Q6ZVM7 TM1L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEFLLGNPFSTPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTVLETCVKNCGHRFHILVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSPDLTGVVHIYEELKRKGVEFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQRTSAGSYSSPPPAPYSAPQAPALSVTGPITANSEQIARLRSELDVVRGNTKVMSEMLTEMVPGQEDSSDLELLQELNRTCRAMQQRIVELISRVSNEEVTEELLHVNDDLNNVFLRYERFERYRSGRSVQNASNGVLNEVTEDNLIDLGPGSPAVVSPMVGNTAPPSSLSSQLAGLDLGTESVSGTLSSLQQCNPRDGFDMFAQTRGNSLAEQRKTVTYEDPQAVGGLASALDNRKQSSEGIPVAQPSVMDDIEVWLRTDLKGDDLEEGVTSEEFDKFLEERAKAAEMVPDLPSPPMEAPAPASNPSGRKKPERSEDALFAL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6ZVM7 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K48 | Ubiquitination | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| S160 | Phosphorylation | Uniprot | |
| T164 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| T177 | Phosphorylation | Uniprot | |
| T187 | Phosphorylation | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| Y200 | Phosphorylation | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| K236 | Ubiquitination | Uniprot | |
| S394 | Phosphorylation | Uniprot | |
| K400 | Ubiquitination | Uniprot | |
| T401 | Phosphorylation | Uniprot | |
| T403 | Phosphorylation | Uniprot | |
| Y404 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| K421 | Ubiquitination | Uniprot | |
| S423 | Phosphorylation | Uniprot | |
| S424 | Phosphorylation | Uniprot | |
| K447 | Ubiquitination | Uniprot | |
| T456 | Phosphorylation | Uniprot | |
| K462 | Ubiquitination | Uniprot | |
| K469 | Ubiquitination | Uniprot | |
| S479 | Phosphorylation | Uniprot |
Research Backgrounds
Probable role in protein transport. May regulate growth factor-induced mitogenic signaling.
Ubiquitously expressed with higher expression in heart and skeletal muscle.
Interacts with clathrin, SRC and TOLLIP.
The GAT domain mediates interaction with TOLLIP.
Belongs to the TOM1 family.
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