SLIRP Antibody - #DF13485
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13485, RRID:AB_2846504.
Fold/Unfold
C14orf156; Chromosome 14 open reading frame 156; DC50; PD04872; SLIRP; SRA stem loop interacting RNA binding protein, mitochondrial;
Immunogens
Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis.
- Q9GZT3 SLIRP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAASAARGAAALRRSINQPVAFVRRIPWTAASSQLKEHFAQFGHVRRCILPFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVKVQVHTRRPKLPQTSDDEKKDF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9GZT3 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| R7 | Methylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| C48 | S-Nitrosylation | Uniprot | |
| K54 | Acetylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| T101 | Phosphorylation | Uniprot | |
| S102 | Phosphorylation | Uniprot |
Research Backgrounds
RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
Mitochondrion. Nucleus.
Note: Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.
Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis.
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