SOX3 Antibody - #DF13521
| Product: | SOX3 Antibody |
| Catalog: | DF13521 |
| Description: | Rabbit polyclonal antibody to SOX3 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Rabbit, Dog |
| Mol.Wt.: | 45kDa; 45kD(Calculated). |
| Uniprot: | P41225 |
| RRID: | AB_2846540 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13521, RRID:AB_2846540.
Fold/Unfold
GHDX; MRGH; PHP; PHPX; sox3; SOX3_HUMAN; SOXB; SRY (sex determining region Y)-box 3; SRY Box 3; SRY-related HMG-box gene 3; Transcription factor Sox-3;
Immunogens
- P41225 SOX3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P41225 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S119 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S380 | Phosphorylation | Uniprot |
Research Backgrounds
Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity).
Nucleus.
Interacts with SOX2 and FGFR1.
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