OVOL2 Antibody - #DF13564
| Product: | OVOL2 Antibody |
| Catalog: | DF13564 |
| Description: | Rabbit polyclonal antibody to OVOL2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 30kDa; 30kD(Calculated). |
| Uniprot: | Q9BRP0 |
| RRID: | AB_2846583 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13564, RRID:AB_2846583.
Fold/Unfold
bA504H3.3; EUROIMAGE566589; hOvo 2; hOvo2; Ovo like 2 (Drosophila); Ovo like 2; ovo-like zinc finger 2; OVOL 2; OVOL2; OVOL2_HUMAN; Transcription factor Ovo like 2; Transcription factor Ovo-like 2; Zinc finger protein 339; ZNF 339; ZNF339;
Immunogens
Expressed in testis, ovary, heart and skeletal muscle (PubMed:12213202). Expressed in the cornea, but absent from the corneal endothelium (PubMed:26749309).
- Q9BRP0 OVOL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKVFLVKRRSLGVSVRSWDELPDEKRADTYIPVGLGRLLHDPPEDCRSDGGSSSGSGSSSAGEPGGAESSSSPHAPESETPEPGDAEGPDGHLATKQRPVARSKIKFTTGTCSDSVVHSCDLCGKGFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCNVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSSFLKKTSKKLAALLQGKLTSAHQENTSLSEEEERK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BRP0 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Methylation | Uniprot | |
| K8 | Methylation | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| Y31 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| Y204 | Phosphorylation | Uniprot | |
| Y206 | Phosphorylation | Uniprot | |
| T266 | Phosphorylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| S269 | Phosphorylation | Uniprot |
Research Backgrounds
Zinc-finger transcription repressor factor. Plays a critical role in maintaining the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition (EMT) mainly through the repression of ZEB1, an EMT inducer (By similarity). Positively regulates neuronal differentiation (By similarity). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1. Important for the correct development of primordial germ cells in embryos (By similarity).
Nucleus.
Expressed in testis, ovary, heart and skeletal muscle. Expressed in the cornea, but absent from the corneal endothelium.
Belongs to the krueppel C2H2-type zinc-finger protein family.
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