PRMT3 Antibody - #DF13606
| Product: | PRMT3 Antibody |
| Catalog: | DF13606 |
| Description: | Rabbit polyclonal antibody to PRMT3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 59kDa; 60kD(Calculated). |
| Uniprot: | O60678 |
| RRID: | AB_2846625 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13606, RRID:AB_2846625.
Fold/Unfold
2010005E20Rik; 2410018A17Rik; AL033309; ANM3_HUMAN; Heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 3; Heterogeneous nuclear ribonucleoprotein methyltransferase like 3; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 3; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HMT1 hnRNP methyltransferase like 3; HMT1 hnRNP methyltransferase like 3 S. cerevisiae; HMT1-like 3; hnRNP methyltransferase like 3; HRMT1L3; PRMT 3; PRMT3; Protein arginine methyltransferase 3; Protein arginine N methyltransferase 3; Protein arginine N-methyltransferase 3;
Immunogens
- O60678 ANM3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCSLASGATGGRGAVENEEDLPELSDSGDEAAWEDEDDADLPHGKQQTPCLFCNRLFTSAEETFSHCKSEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O60678 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C2 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| K81 | Methylation | Uniprot | |
| Y87 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| R178 | Methylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| R200 | Methylation | Uniprot | |
| Y248 | Phosphorylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| Y387 | Phosphorylation | Uniprot | |
| K396 | Ubiquitination | Uniprot | |
| K410 | Ubiquitination | Uniprot | |
| C417 | S-Nitrosylation | Uniprot | |
| K477 | Acetylation | Uniprot | |
| K477 | Ubiquitination | Uniprot | |
| T525 | Phosphorylation | Uniprot | |
| T527 | Phosphorylation | Uniprot |
Research Backgrounds
Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins.
Cytoplasm.
Monomer or homodimer (By similarity). Interacts with EPB41L3; this inhibits methylation of target proteins. Interacts with the 40S ribosomal protein RPS2.
The zinc-finger is responsible for substrate specificity.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
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