GLUT12 Antibody - #DF13649
| Product: | GLUT12 Antibody |
| Catalog: | DF13649 |
| Description: | Rabbit polyclonal antibody to GLUT12 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 66kDa; 67kD(Calculated). |
| Uniprot: | Q8TD20 |
| RRID: | AB_2846668 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13649, RRID:AB_2846668.
Fold/Unfold
Glucose transporter type 12; GLUT 12; GLUT-12; GLUT12; GLUT8; GTR12_HUMAN; SLC2A12; Solute carrier family 2 (facilitated glucose transporter) member 12; Solute carrier family 2 facilitated glucose transporter member 12; Solute carrier family 2 member 12; Solute carrier family 2, facilitated glucose transporter member 12;
Immunogens
Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney.
- Q8TD20 GTR12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLECNKLCGRGQSRQLSPET
PTMs - Q8TD20 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T18 | Phosphorylation | Uniprot | |
| T22 | Phosphorylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| T108 | Phosphorylation | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| Y198 | Phosphorylation | Uniprot | |
| Y215 | Phosphorylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| S312 | Phosphorylation | Uniprot | |
| T432 | O-Glycosylation | Uniprot | |
| T433 | O-Glycosylation | Uniprot | |
| S434 | O-Glycosylation | Uniprot | |
| T445 | O-Glycosylation | Uniprot |
Research Backgrounds
Insulin-independent facilitative glucose transporter.
Cell membrane>Multi-pass membrane protein. Endomembrane system>Multi-pass membrane protein. Cytoplasm>Perinuclear region.
Note: Localizes primarily perinuclear region in the absence of insulin.
Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney.
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
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