PRRG4 Antibody - #DF13694
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13694, RRID:AB_2846713.
Fold/Unfold
9930111I18Rik; MGC117538; Proline-rich gamma-carboxyglutamic acid protein 4; Proline-rich Gla protein 4; PRRG 4; PRRG4; TMG4; TMG4_HUMAN; Transmembrane gamma-carboxyglutamic acid protein 4;
Immunogens
- Q9BZD6 TMG4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFTLLVLLSQLPTVTLGFPHCARGPKASKHAGEEVFTSKEEANFFIHRRLLYNRFDLELFTPGNLERECNEELCNYEEAREIFVDEDKTIAFWQEYSAKGPTTKSDGNREKIDVMGLLTGLIAAGVFLVIFGLLGYYLCITKCNRLQHPCSSAVYERGRHTPSIIFRRPEEAALSPLPPSVEDAGLPSYEQAVALTRKHSVSPPPPYPGHTKGFRVFKKSMSLPSH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BZD6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S38 | Phosphorylation | Uniprot | |
| T102 | Phosphorylation | Uniprot | |
| T103 | Phosphorylation | Uniprot | |
| Y155 | Phosphorylation | Uniprot | |
| T161 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| S222 | Phosphorylation | Uniprot |
Research Backgrounds
May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression.
Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.
Endoplasmic reticulum-Golgi intermediate compartment membrane>Single-pass membrane protein.
Expressed in lung, liver, kidney, pancreas and placenta.
Belongs to the commissureless family.
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