tenomodulin Antibody - #DF13715

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Product: tenomodulin Antibody
Catalog: DF13715
Description: Rabbit polyclonal antibody to tenomodulin
Application: WB IHC
Cited expt.:
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 37kDa; 37kD(Calculated).
Uniprot: Q9H2S6
RRID: AB_2846734

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
tenomodulin Antibody detects endogenous levels of total tenomodulin.
RRID:
AB_2846734
Cite Format: Affinity Biosciences Cat# DF13715, RRID:AB_2846734.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BRICD4; BRICHOS domain containing 4; CHM1 LIKE; ChM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TeM; Tendin; Tenomodulin; Tenomodulin protein; Tnmd; TNMD_HUMAN; UNQ771/PRO1565;

Immunogens

Immunogen:

A synthesized peptide derived from human tenomodulin, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9H2S6(TNMD_HUMAN) >>Visit HPA database.

Gene(ID):
TNMD(64102)
Expression:
Q9H2S6 TNMD_HUMAN:

Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.

Sequence:
MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Zebrafish
75
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

Research Backgrounds

Function:

May be an angiogenesis inhibitor.

Subcellular Location:

Membrane>Single-pass type II membrane protein. Nucleus envelope.

Membrane>Single-pass type II membrane protein. Nucleus envelope.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.

Family&Domains:

Belongs to the chondromodulin-1 family.

References

1). Natural fish swim bladder-derived MPN-nanofibrous biomimetic system exhibit ECM-responsive signal regulation and promote robust tendon-bone healing. Journal of nanobiotechnology, 2025 (PubMed: 40618081) [IF=10.2]

Application: IF/ICC    Species: Rat    Sample: BMSCs

Fig. 5 The impact of GaPP@FSB on the differentiation of BMSCs, Chondrocytes and TSPCs. Confocal laser scanning microscopy (CLSM) images showing fluorescence-labelled (A) OPN in the BMSCs (scale bar = 200 μm), and the Q-PCR data (B) revealed the expression of osteogenic differentiation-related genes in BMSCs cultured on the GaPP@FSB scaffold. Additionally, the CLSM images also showed the fluorescence-labelled (C) Tnmd in TSPCs (bar 100 μm), and Q-PCR data (D) revealed the expression of tenogenic differentiation-related genes in TSPCs cultured on the GaPP@FSB scaffold. The investigation approach for the influence of scaffolds on chondrocytes is uniform. (E) CLSM reveals the level of ACAN, a chondrocyte matrix-related proteoglycan, and (F) the Q-PCR results demonstrate the expression of genes related to chondrogenic differentiation. Data are presented as mean values ± SD, *p 
2). Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair. ACS applied materials & interfaces, 2025 (PubMed: 40675622) [IF=8.3]

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