NSBP1 Antibody - #DF13802

Product: NSBP1 Antibody
Catalog: DF13802
Description: Rabbit polyclonal antibody to NSBP1
Application: ELISA(peptide)
Reactivity: Human
Mol.Wt.: 51kD; 32kD(Calculated).
Uniprot: P82970

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
NSBP1 Antibody detects endogenous levels of total NSBP1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

High mobility group nucleosome binding domain 5; High mobility group nucleosome-binding domain-containing protein 5; Hmgn5; HMGN5_HUMAN; NBP 45; NSBP 1; NSBP1; Nucleosomal binding protein 1; Nucleosome binding protein 1; Nucleosome-binding protein 1;

Immunogens

Immunogen:

A synthesized peptide derived from Human NSBP1.

Uniprot:

P82970(HMGN5_HUMAN) >>Visit HPA database.

Gene(ID):
HMGN5(79366)
Expression:
P82970 HMGN5_HUMAN:

Ubiquitously expressed.

Sequence:
MPKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSIV

Research Backgrounds

Function:

Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction.

Subcellular Location:

Nucleus.
Note: Associates with nucleosomes in euchromatin and is largely excluded from constitutive heterochromatin.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitously expressed.

Family&Domains:

Specifically targeted by its C-terminus to nucleosomes in euchromatin.

Belongs to the HMGN family.

Restrictive clause

 

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