NAA60 Antibody - #DF13864
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
FLJ11693; FLJ14154; HAT4; Histone acetyltransferase type B protein 4; N acetyltransferase 15 (GCN5 related, putative); N alpha acetyltransferase 60; N(alpha) acetyltransferase 60, NatF catalytic subunit; N-acetyltransferase 15; N-alpha-acetyltransferase 60; naa60; NAA60_HUMAN; NAT15; NatF catalytic subunit;
Immunogens
A synthesized peptide derived from Human FLJ14154.
- Q9H7X0 NAA60_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTEVVPSSALSEVSLRLLCHDDIDTVKHLCGDWFPIEYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKEDGDILASNFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNTAINFYENRDFKQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALASLSPCSIPHRVYRQAHSLLCSFLPWSGISSKSGIEYSRTM
Research Backgrounds
N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences.
Acetylated: autoacetylation is required for optimal acetyltransferase activity.
Golgi apparatus membrane>Peripheral membrane protein>Cytoplasmic side.
Note: Probably forms an intramembrane hairpin-like structure in the membrane.
Monomer and homodimer; monomer in presence of substrate and homodimer in its absence.
Belongs to the acetyltransferase family. NAA60 subfamily.
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