Product: Protease Inhibitor 15 Antibody
Catalog: DF13876
Description: Rabbit polyclonal antibody to Protease Inhibitor 15
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 30kD; 29kD(Calculated).
Uniprot: O43692

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
Protease Inhibitor 15 Antibody detects endogenous levels of total Protease Inhibitor 15.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

25 kDa trypsin inhibitor; CRISP-8; CRISP8; Cysteine rich secretory protein 8; Cysteine-rich secretory protein 8; P24TI; p25TI; Peptidase inhibitor 15; PI-15; PI15; PI15_HUMAN; Protease Inhibitor 15; SugarCrisp;

Immunogens

Immunogen:

A synthesized peptide derived from Human Protease Inhibitor 15.

Uniprot:
Gene(ID):
Expression:
O43692 PI15_HUMAN:

Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland.

Sequence:
MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK

Research Backgrounds

Function:

Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity).

PTMs:

N-glycosylated.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland.

Family&Domains:

Belongs to the CRISP family.

Restrictive clause

 

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