Product: SLC10A1 Antibody
Catalog: DF13906
Description: Rabbit polyclonal antibody to SLC10A1
Application: ELISA(peptide)
Reactivity: Human
Mol.Wt.: 38~55kD; 38kD(Calculated).
Uniprot: Q14973

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
SLC10A1 Antibody detects endogenous levels of total SLC10A1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cell growth-inhibiting gene 29 protein; GIG29; Growth inhibiting protein 29; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Na/taurocholate cotransporting polypeptide; NTCP; NTCP_HUMAN; NTCP1; SLC10A1; Sodium/bile acid cotransporter; Sodium/taurocholate cotransporter polypeptide, hepatic; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 (sodium/bile acid cotransporter family) member 1; Solute carrier family 10 member 1;

Immunogens

Immunogen:

A synthesized peptide derived from Human SLC10A1.

Uniprot:
Gene(ID):
Sequence:
MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKGLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSIVMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSKRPQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVLSALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLLIAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA

Research Backgrounds

Function:

The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.

(Microbial infection) Acts as a receptor for hepatitis B virus.

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

(Microbial infection) Interacts with hepatitis B virus large envelope protein.

Family&Domains:

Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.

Restrictive clause

 

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