Product: TRIM17 Antibody
Catalog: DF13958
Description: Rabbit polyclonal antibody to TRIM17
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 54kD; 54kD(Calculated).
Uniprot: Q9Y577

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
TRIM17 Antibody detects endogenous levels of total TRIM17.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

E3 ubiquitin-protein ligase TRIM17; RBCC; RING finger protein 16; RING finger protein terf; RNF16; TERF; Testis RING finger protein; TRI17_HUMAN; TRIM 17; Trim17; Tripartite motif containing 17; Tripartite motif containing protein 17; Tripartite motif protein 17; Tripartite motif-containing protein 17;

Immunogens

Immunogen:

A synthesized peptide derived from Human TRIM17.

Uniprot:
Gene(ID):
Expression:
Q9Y577 TRI17_HUMAN:

Almost exclusively in the testis.

Sequence:
MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWVKG

Research Backgrounds

Function:

May function as a ubiquitin E3 ligase.

PTMs:

Auto-ubiquitinated.

Tissue Specificity:

Almost exclusively in the testis.

Subunit Structure:

Interacts (via coiled coil) with TRIM44 (via coiled coil).

Family&Domains:

Belongs to the TRIM/RBCC family.

Restrictive clause

 

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