CCNO Antibody - #DF14008

(3)  
Product: CCNO Antibody
Catalog: DF14008
Description: Rabbit polyclonal antibody to CCNO
Application: WB IHC IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 38kD; 38kD(Calculated).
Uniprot: P22674

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
CCNO Antibody detects endogenous levels of total CCNO.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CCNO; CCNO_HUMAN; CCNU; Cyclin domain containing; Cyclin like uracil DNA glycosylase; Cyclin O; Cyclin U; Cyclin-O; DGU; EC 3.2.2.; UDG2; UNG2; Uracil DNA glycolylase 2; Uracil DNA glycosylase cyclin like;

Immunogens

Immunogen:

A synthesized peptide derived from Human CCNO.

Uniprot:

P22674(CCNO_HUMAN) >>Visit HPA database.

Gene(ID):
CCNO(10309)
Expression:
P22674 CCNO_HUMAN:

Present in respiratory cells (at protein level).

Sequence:
MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK

Research Backgrounds

Function:

Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.

Subcellular Location:

Cytoplasm.
Note: Localizes to the apical part of cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Present in respiratory cells (at protein level).

Family&Domains:

Belongs to the cyclin family.

Restrictive clause

 

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