ZNF580 Antibody - #DF14026

Product: ZNF580 Antibody
Catalog: DF14026
Description: Rabbit polyclonal antibody to ZNF580
Application: ELISA(peptide)
Reactivity: Human, Mouse, Rat
Mol.Wt.: 19kD; 19kD(Calculated).
Uniprot: Q9UK33

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
ZNF580 Antibody detects endogenous levels of total ZNF580.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

LDL induced EC protein; LDL-induced EC protein; Zinc finger protein 580; ZN580_HUMAN; Znf580;

Immunogens

Immunogen:

A synthesized peptide derived from Human ZNF580.

Uniprot:

Q9UK33(ZN580_HUMAN) >>Visit HPA database.

Gene(ID):
ZNF580(51157)
Expression:
Q9UK33 ZN580_HUMAN:

Expressed in endothelial cells.

Sequence:
MLLLPPRPPHPRSSSPEAMDPPPPKAPPFPKAEGPSSTPSSAAGPRPPRLGRHLLIDANGVPYTYTVQLEEEPRGPPQREAPPGEPGPRKGYSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCPRRFQDAAELAQHVRLH

Research Backgrounds

Function:

Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation. May be involved in transcriptional regulation.

Subcellular Location:

Nucleus.
Note: Colocalized with SMAD2 in the nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in endothelial cells.

Subunit Structure:

Interacts with SMAD2.

Restrictive clause

 

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