beta 4 Defensin Antibody - #DF14053

(2)  
Product: beta 4 Defensin Antibody
Catalog: DF14053
Description: Rabbit polyclonal antibody to beta 4 Defensin
Application: IHC IF/ICC
Reactivity: Human
Mol.Wt.: 9kD(Calculated).
Uniprot: Q8WTQ1

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Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
beta 4 Defensin Antibody detects endogenous levels of total beta 4 Defensin.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BD 4; BD-4; BD4; beta 104; beta 4 Defensin; Beta defensin 4; Beta-defensin 104; Beta-defensin 4; D104A_HUMAN; DEFB-4; DEFB104B; Defensin; Defensin beta 104; Defensin beta 4 precursor; hBD 4; hBD-4; hBD4;

Immunogens

Immunogen:

A synthesized peptide derived from Human beta 4 Defensin.

Uniprot:

Q8WTQ1(D104A_HUMAN) >>Visit HPA database.

Gene(ID):
DEFB104A; DEFB104B(140596)
Expression:
Q8WTQ1 D104A_HUMAN:

High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.

Sequence:
MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP

Research Backgrounds

Function:

Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.

Family&Domains:

Belongs to the beta-defensin family.

Restrictive clause

 

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