HELT Antibody - #DF14188

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Product: HELT Antibody
Catalog: DF14188
Description: Rabbit polyclonal antibody to HELT
Application: IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 27kD(Calculated).
Uniprot: A6NFD8

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
HELT Antibody detects endogenous levels of total HELT.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Hairy and enhancer of split-related protein HELT; HCM1228; HELT; HELT_HUMAN; HES like; HES/HEY like transcription factor; HES/HEY-like transcription factor; HESL; Heslike; Hey like transcription factor; Hey like transcription factor (zebrafish); Hey like transcriptional repressor; Megane bHLH factor; Mgn;

Immunogens

Immunogen:

A synthesized peptide derived from Human HELT.

Uniprot:

A6NFD8(HELT_HUMAN) >>Visit HPA database.

Gene(ID):
HELT(391723)
Sequence:
MSDKLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAHPNALNLHTPQHPPVL

Research Backgrounds

Function:

Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Self-associates. Interacts with HES5 and HEY2 (By similarity).

Family&Domains:

Belongs to the HEY family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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