Melanoma Inhibitory Activity Antibody - #DF14235

(2)  
Product: Melanoma Inhibitory Activity Antibody
Catalog: DF14235
Description: Rabbit polyclonal antibody to Melanoma Inhibitory Activity
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 15kD(Calculated).
Uniprot: Q16674

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
Melanoma Inhibitory Activity Antibody detects endogenous levels of total Melanoma Inhibitory Activity.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cartilage derived retinoic acid sensitive protein; CD RAP; CDRAP; Melanoma derived growth regulatory protein precursor; Melanoma inhibitory activity protein; Melanoma-derived growth regulatory protein; Mia; MIA_HUMAN;

Immunogens

Immunogen:

A synthesized peptide derived from Human Melanoma Inhibitory Activity.

Uniprot:

Q16674(MIA_HUMAN) >>Visit HPA database.

Gene(ID):
MIA(8190)
Expression:
Q16674 MIA_HUMAN:

All malignant melanoma cell lines tested and infrequently in glioma cell lines.

Sequence:
MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ

Research Backgrounds

Function:

Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.

PTMs:

May possess two intramolecular disulfide bonds.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

All malignant melanoma cell lines tested and infrequently in glioma cell lines.

Subunit Structure:

Interacts with FASLG. Interacts with TMIGD2.

Family&Domains:

Belongs to the MIA/OTOR family.

Restrictive clause

 

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