RSL1D1 Antibody - #DF14381

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Product: RSL1D1 Antibody
Catalog: DF14381
Description: Rabbit polyclonal antibody to RSL1D1
Application: WB
Reactivity: Human, Rat
Mol.Wt.: 55kD(Calculated).
Uniprot: O76021

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
RSL1D1 Antibody detects endogenous levels of total RSL1D1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; Cellular senescence-inhibited gene protein; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain containing 1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; RSL1D1; UTP30;

Immunogens

Immunogen:

A synthesized peptide derived from Human RSL1D1.

Uniprot:

O76021(RL1D1_HUMAN) >>Visit HPA database.

Gene(ID):
RSL1D1(26156)
Expression:
O76021 RL1D1_HUMAN:

Expressed at high intensities in the heart, skeletal muscle, and placenta.

Sequence:
MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLNENESLFLMVVLWKIPSKELRVRLTLPHSIRSDSEDICLFTKDEPNSTPEKTEQFYRKLLNKHGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIGRHFYQRKKVPVSVNLLSKNLSREINDCIGGTVLNISKSGSCSAIRIGHVGMQIEHIIENIVAVTKGLSEKLPEKWESVKLLFVKTEKSAALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST

Research Backgrounds

Function:

Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.

Subcellular Location:

Nucleus>Nucleolus.
Note: Colocalizes with ING1 in the nucleolus after UV stress.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed at high intensities in the heart, skeletal muscle, and placenta.

Subunit Structure:

Interacts with ING1 (isoform 2).

Family&Domains:

Belongs to the universal ribosomal protein uL1 family. Highly divergent.

Restrictive clause

 

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