ALS2CR2 Antibody - #DF14383
Product: | ALS2CR2 Antibody |
Catalog: | DF14383 |
Description: | Rabbit polyclonal antibody to ALS2CR2 |
Application: | ELISA(peptide) |
Reactivity: | Human, Mouse, Rat |
Mol.Wt.: | 35~50kD; 47kD(Calculated). |
Uniprot: | Q9C0K7 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
ALS2 chromosome region gene 2; ALS2CR2; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; CALS 21; CALS-21; ILP interacting protein ILPIPA; ILP-interacting protein; ILPIP; ILPIPA; Likely ortholog of mouse polyploidy associated protein kinase; PAPK; PRO1038; Pseudokinase ALS2CR2; STE20-related kinase adapter protein beta; STRAB_HUMAN; STRAD beta; STRADB;
Immunogens
A synthesized peptide derived from Human ALS2CR2.
- Q9C0K7 STRAB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
Research Backgrounds
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
Nucleus. Cytoplasm.
Highly expressed in heart, skeletal muscle, testis, liver and colon.
The protein kinase domain is predicted to be catalytically inactive.
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Research Fields
· Environmental Information Processing > Signal transduction > mTOR signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > AMPK signaling pathway. (View pathway)
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