N myc interactor Antibody - #DF14405

(3)  
Product: N myc interactor Antibody
Catalog: DF14405
Description: Rabbit polyclonal antibody to N myc interactor
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 35~40kD; 35kD(Calculated).
Uniprot: Q13287

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
N myc interactor Antibody detects endogenous levels of total N myc interactor.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

N myc (and STAT) interactor; N myc and STAT interactor; N myc interactor; NMI; NMYC and STAT interactor; NMYC interactor;

Immunogens

Immunogen:

A synthesized peptide derived from Human N myc interactor.

Uniprot:

Q13287(NMI_HUMAN) >>Visit HPA database.

Gene(ID):
NMI(9111)
Expression:
Q13287 NMI_HUMAN:

Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.

Sequence:
MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQIKEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVSMSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTEIHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQPHIAYFEE

Research Backgrounds

Function:

May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.

Subunit Structure:

Interacts with MYCN and MYC, as well as with other transcription factors with a Zip, HLH or a HLH-Zip motif. Interacts with all STAT proteins except STAT2.

Family&Domains:

Belongs to the NMI family.

Restrictive clause

 

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