TCEA2 Antibody - #DF14578

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Product: TCEA2 Antibody
Catalog: DF14578
Description: Rabbit polyclonal antibody to TCEA2
Application: WB
Reactivity: Human, Mouse, Rat
Mol.Wt.: 34kD(Calculated).
Uniprot: Q15560

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
TCEA2 Antibody detects endogenous levels of TCEA2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Tcea2; TCEA2_HUMAN; Testis specific S II; Testis-specific S-II; TFIIS; Transcription elongation factor A (SII) 2; Transcription elongation factor A 2; Transcription elongation factor A protein 2; Transcription elongation factor S II protein 2; Transcription elongation factor S-II protein 2; Transcription elongation factor TFIIS.1; Transcription elongation factor TFIIS.l;

Immunogens

Immunogen:

A synthesized peptide derived from human TCEA2.

Uniprot:

Q15560(TCEA2_HUMAN) >>Visit HPA database.

Gene(ID):
TCEA2(6919)
Expression:
Q15560 TCEA2_HUMAN:

Testis and ovary specific.

Sequence:
MMGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPITLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLDASDAKARERGRGMPLPTSSRDASEAPDPSRKRPELPRAPSTPRITTFPPVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC

Research Backgrounds

Function:

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Testis and ovary specific.

Subunit Structure:

Interacts with the basal transcription factor GTF2B. Interacts with REXO1.

Family&Domains:

Belongs to the TFS-II family.

Restrictive clause

 

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For Research Use Only.
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