MSRB1 Antibody - #DF14643

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Product: MSRB1 Antibody
Catalog: DF14643
Description: Rabbit polyclonal antibody to MSRB1
Application: IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 13kD(Calculated).
Uniprot: Q9NZV6

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
MSRB1 Antibody detects endogenous levels of MSRB1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Annexin A2 like; EC 1 8 4; HSPC 270; HSPC270; Methionine R sulfoxide reductase; Methionine R sulfoxide reductase B1; Methionine sulfoxide reductase; Methionine-R-sulfoxide reductase B1; MGC3344; MSRB 1; MsrB1; MSRB1_HUMAN; OTTHUMP00000159418; Sel X; Selenoprotein R; Selenoprotein X 1; Selenoprotein X; Selenoprotein X1; SELR; SelX; SEPX 1; sepx1;

Immunogens

Immunogen:

A synthesized peptide derived from human MSRB1.

Uniprot:

Q9NZV6(MSRB1_HUMAN) >>Visit HPA database.

Gene(ID):
MSRB1(51734)
Sequence:
MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSRSKYAHSSPWPAFTETIHADSVAKRPEHNRSEALKVSCGKCGNGLGHEFLNDGPKPGQSRFUIFSSSLKFVPKGKETSASQGH

Research Backgrounds

Function:

Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.

Subcellular Location:

Cytoplasm. Nucleus. Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the MsrB Met sulfoxide reductase family.

Restrictive clause

 

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