Product: ARHGEF9 Antibody
Catalog: DF14646
Description: Rabbit polyclonal antibody to ARHGEF9
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 61kD(Calculated).
Uniprot: O43307

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
ARHGEF9 Antibody detects endogenous levels of ARHGEF9.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

9630036L12Rik; A230067K14; ARHG9_HUMAN; Arhgef9; Cdc42 guanine nucleotide exchange factor (GEF) 9; Collybistin; collybistin I; EIEE8; HPEM 2; hPEM-2 collybistin; KIAA0424; mKIAA0424; OTTHUMP00000023424; OTTHUMP00000023425; OTTHUMP00000023427; PEM 2; PEM 2 homolog; PEM-2 homolog; PEM2; Rac/Cdc42 guanine nucleotide exchange factor 9; Rho guanine nucleotide exchange factor 9; RP11 357C3.4; RP23 230K20.3;

Immunogens

Immunogen:

A synthesized peptide derived from human ARHGEF9.

Uniprot:
Gene(ID):
Expression:
O43307 ARHG9_HUMAN:

Detected in brain. Detected at low levels in heart.

Sequence:
MTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQEDEVEEGPSDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQAAMTVRKVPKQKGVNSARSVPPSYPPPQDPLNHGQYLVPDGIAQSQVFEFTEPKRSQSPFWQNFSRLTPFKK

Research Backgrounds

Function:

Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity).

Subcellular Location:

Cytoplasm. Cell junction>Synapse>Postsynaptic density.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in brain. Detected at low levels in heart.

Subunit Structure:

Interacts with GPHN.

Restrictive clause

 

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