Product: AKIRIN1 Antibody
Catalog: DF14690
Description: Rabbit polyclonal antibody to AKIRIN1
Application: ELISA(peptide)
Reactivity: Human
Mol.Wt.: 22kD(Calculated).
Uniprot: Q9H9L7

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
AKIRIN1 Antibody detects endogenous levels of AKIRIN1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AKIR1_HUMAN; AKIRIN 1; Akirin-1; Akirin1; C1orf108; FLJ12666; OTTHUMP00000008669; RP11-781D11.2; STRF2;

Immunogens

Immunogen:

A synthesized peptide derived from human AKIRIN1.

Uniprot:
Gene(ID):
Expression:
Q9H9L7 AKIR1_HUMAN:

Widely expressed with the highest expression in heart, liver, placenta and peripheral blood leukocytes.

Sequence:
MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPPDAEPPPPFQTQTPPQSLQQPAPPGSERRLPTPEQIFQNIKQEYSRYQRWRHLEVVLNQSEACASESQPHSSALTAPSSPGSSWMKKDQPTFTLRQVGIICERLLKDYEDKIREEYEQILNTKLAEQYESFVKFTHDQIMRRYGTRPTSYVS

Research Backgrounds

Function:

Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis. May regulate chemotaxis of both macrophages and myoblasts by reorganising actin cytoskeleton, leading to more efficient lamellipodia formation via a PI3 kinase dependent pathway.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed with the highest expression in heart, liver, placenta and peripheral blood leukocytes.

Family&Domains:

Belongs to the akirin family.

Restrictive clause

 

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