MINOS1 Antibody - #DF14761
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
Chromosome 1 open reading frame 151; FLJ36999; FLJ75158; MINOS1; Mitochondrial inner membrane organizing system 1; RP5-1056L3.2; UPF0327 protein C1orf151;
Immunogens
A synthesized peptide derived from human MINOS1.
- Q5TGZ0 MIC10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAPYLLHGKYVKEQEQ
Research Backgrounds
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Mitochondrion inner membrane>Single-pass membrane protein.
Note: The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (PubMed:22114354).
Belongs to the MICOS complex subunit Mic10 family.
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